Coding

Part:BBa_K5313010

Designed by: Xiangyu Gu   Group: iGEM24_NEFU-China   (2024-09-25)


One of the two parts of formaldehyde dehydrogenase.

The frmA gene encodes formaldehyde dehydrogenase, a key enzyme involved in formaldehyde metabolism in Escherichia coli. The gene product catalyzes the conversion of formaldehyde to formate, thereby reducing formaldehyde toxicity within the cell. This makes the frmA gene a promising candidate for applications in formaldehyde degradation and environmental pollution control. In synthetic biology projects, the frmA gene can be utilized to design engineered bacterial strains capable of degrading formaldehyde, which can be employed in bioremediation processes, such as the treatment of industrial wastewater. By introducing the frmA gene into an E. coli expression system, users can endow the cells with the ability to metabolize and detoxify formaldehyde.

< img style="margin:20px auto 5px auto;" src="https://static.igem.wiki/teams/5313/parts/frmab-fdh.png" width="80%">

Mechanism diagram

Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    INCOMPATIBLE WITH RFC[25]
    Illegal NgoMIV site found at 193
    Illegal AgeI site found at 517
  • 1000
    COMPATIBLE WITH RFC[1000]


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Categories
Parameters
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